Manchester United's annual trip to Anfield is the side's third fixture next season.
Liverpool have always represented stern adversaries for the Red Devils over the years, both in the Premier League and in domestic competition.
There have been close contests, blowouts, and plenty of highlight-reel-worthy goals.
This article will bring together 10 of the most memorable Manchester United strikes in games against Liverpool.
Fans of the Reds look away now.
First up is John O'Shea's dramatic late winner against the Reds in 2007.
The strike gave Manchester United a vital 1-0 win late in what proved to be a triumphant season.
The game itself was fraught and fiery. Paul Scholes received his marching orders in the second half for a swipe at Xabi Alonso.
O'Shea's goal capped a truly smash-and-grab effort.
Manchester United did the league double over Liverpool last term, triumphing 2-1 in both home and away fixtures.
The earlier season clash at Anfield saw United full-back Rafael score a beauty past Pepe Reina.
Receiving the ball from a neat Shinji Kagawa chest-down, the Brazilian took a touch and then struck a curling effort that cannoned in off the post.
We journey a little further back in time for our third effort—Lou Macari's FA Cup-winning goal in 1977.
The Red Devils beat Liverpool 2-1 at Wembley, with the crucial strike coming courtesy of the Scottish midfielder in the 55th minute.
His shot may have deflected off Jimmy Greenhoff's chest, but Macari rightfully claimed the famous goal.
Returning from a nine-month suspension for attacking a fan, Eric Cantona marked his comeback in dramatic style in October, 1995.
A late penalty conversion to tie a clash with Liverpool at 2-2 sent him flying past the goal to swing on the stanchion.
United went on to win the Premier League that season, backed by Cantona's 14 goals.
Later that same season, the enigmatic Frenchman outdid himself, scoring the winner in the 1996 FA Cup final.
Liverpool were the opponents and Wembley Stadium the setting for one of the greatest goals in FA Cup history.
Eric Cantona's adroit volley through a packed crowd of Reds was one of the defining moments of his career.
Wayne Rooney scored a clinical double in February last year to down a plucky Liverpool side.
His first in the 2-1 win was a snap reaction following a Ryan Giggs corner. The second was a slotted effort under the legs of Reina.
Rooney may not currently be the most popular man in Manchester, but his double to down the Reds remains a fond memory.
Dimitar Berbatov, the £30 million man, is largely thought of as a flop signing under Sir Alex Ferguson.
However, he did put in some outstanding displays during his time at Old Trafford, most notably his hat-trick to single-handedly beat Liverpool in 2010.
The second was the pick of the goals. An acrobatic overhead kick past—you guessed it—a stricken Pepe Reina.
Rio Ferdinand is not usually known for his goal-scoring exploits, but the central defender scored a vital one against Liverpool in 2006.
The Reds were actually the better team in the January clash, with the Red Devils missing Cristiano Ronaldo due to suspension.
But late in the game, Rio lept to head home a powerful header, sending Gary Neville into now infamous celebration.
Down 3-1 at halftime, Manchester United staged an epic second-half comeback to tie Liverpool 3-3 in a 1988 First Division clash.
Bryan Robson scored the Red Devils' second, before diminutive winger Gordon Strachan popped up to calmly slot home an equaliser late on.
That season, Sir Alex Ferguson's side finished runners-up to Liverpool in the league, though.
Manchester United's 1998/99 treble-winning season was full of dramatic last-gasp winners.
Down a goal-to-nil late in an FA Cup clash with Liverpool, a Dwight Yorke tap-in and a slotted Ole Gunnar Solskjaer finish sent the Old Trafford faithful into delirium.
Fittingly, it was the Norwegian striker who scored the Red Devils' final goal of the campaign in the Champions League final as well.