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Amir Khan would present an opportunity for Mayweather to expand his reach overseas.
While Mayweather would be a heavy favorite against Amir Khan, the fight would serve several notable purposes.
First, Mayweather is rumored to have interest in showcasing his skills across the pond. Unless he plans on bringing a dance partner along with him, Khan is the best option simply because of his size and star power.
Next, Khan's amazingly fast hands and long arms would present Mayweather a puzzle he hasn't quite seen before. Talent-wise, Khan is world class. Could he keep Mayweather busy enough defending himself via shoulder roll to keep his shaky chin out of harm's way?
Finally, the fight would be just plain enjoyable to watch. Mayweather's skills are always a pleasure for fight fans to behold, and Amir Khan seems to be incapable of being in a boring fight. He's either looking flashy or trying to stay from laying flat on his back.
That's just good television, folks.