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Bjoern Werner (outside linebacker from Florida State at No. 24) and Montori Hughes (defensive tackle from Tennessee-Martin at No. 139) aren't complete players, but both have a chance to do some damage is Chuck Pagano's defense. They'll have great teachers and enough leash to learn from mistakes on the field.
Hugh Thornton (offensive guard from Illinois at No. 86) and Khaled Holmes (center from USC at No. 121) were both huge reaches on my board, but were also top-ranked players when taking the zone-blocking scheme into account.
While Bruce Arians preferred a man/power-blocking approach, Pep Hamilton ran a lot of ZBS as the "Andrew Luck Director of Offense" at Stanford and is clearly bringing that scheme to the pros. Late-round back Kerwynn Williams (Utah State at No. 230) fits the ZBS as well.
My two favorite picks of the class, however, might be John Boyett (strong safety from Oregon at No. 192) and Mr. Irrelevant himself, Justice Cunningham (tight end from South Carolina at No. 254)—both late-rounders.
Boyett was the Oregon Ducks' leading tackler in 2011 before an injury sidelined him in September last season. He has a chance to be a great in-the-box safety or a core special teamer. As for Mr. Irrelevant, Justice Cunningham, he's already the best blocking tight end on the Colts roster.
It would not be surprising to see an impact from every single member of this Colts draft class.