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It's not that Marquise Goodwin has no chance of becoming a good player. If he's used right, a team will be thrilled with his ability to make big plays.
One problem is, he's undersized at 5'7" and 178 pounds, and with a lack of functional strength, there are questions as to whether he has the physicality necessary to handle press coverage at the line of scrimmage and catches in traffic.
Another problem is, he has limited football experience, and his primary sport was track until recently. There are more questions as to whether he will develop into a true football player with time, or fail to shed his label as a "track star playing football."
With time, we'll have our answers, but right now, there's not much that's different about Goodwin compared to wide receiver T.J. Graham, another small former track star playing for the Bills, who was also drafted in the third round last year.