With Reading and Queens Park Rangers going down, according to skybet.com, there is just one spot remaining in the relegation battle.
And there are seven teams all within eight points of each other, for whom a couple of poor games could mean the drop from the top.
However there are four matches this weekend that could either increase that gap or drag these teams closer together. And those involve the teams sat between 13th and 18th.
But what are the most important battles of the Premier League weekend? Read on to find out.
All fixtures, results and league positions taken from BBC.