Howard led the way with a ridiculously impressive 26 points, 17 rebounds, three blocks and two steals.
Steve Blake did his best Kobe impersonation, with 23 points on 50 percent shooting, with five rebounds and four assists.
The Spurs just couldn't overcome the Lakers hustle on defense and their opportunistic shooting on offense.
While both teams shot under 40 percent—Spurs (37.1 percent), Lakers (36.5 percent)—the real difference maker was the six-rebound advantage the Lakers had over the Spurs on the offensive glass.
No one besides Jodie Meeks, Steve Blake and Antawn Jamison hit a deep ball, but the ones those players hit all came at just the right time.
The Lakers held Tony Parker to just four points on 1-of-10 shooting. Tim Duncan did all he could with 23 points on 50 percent shooting, with 10 rebounds.
All in all, it was clear that the Lakers wanted to show the world that they can still win without Kobe. And they did just that.
Next up is a essentially a playoff game against the Houston Rockets on Wednesday night in L.A. With a win, the Lake Show will be playoff bound. With a loss, the Lakers' playoff future will depend on the Utah Jazz.