The Citizens skipper is reportedly at odds with Mancini after disobeying his managers wishes to not play for Belgium during the recent international fixtures.
Kompany had not featured for his club since the middle of January following a calf injury, but played the whole 90 minutes of Belgium's World Cup qualification victory over Macedonia last Tuesday.
Mancini is thought to be less than impressed with the conduct of his captain and didn't hide his displeasure at a recent press conference.
"I am not saying the national team is not important, and I would never tell my players not to go to play for their country. But there are some cases when the club is more important, and all players should understand this.
“I expected that he wouldn’t play, and that he would be back after one or two days. Instead, he played for 90 minutes and now we don’t know his condition.”
Belgian newspaper Het Nieuwsblad claim Kompany is annoyed that Manicini went public with the issue, and he wouldn't be the first City player to fall out with the fiery Italian.
The storm may blow over in the next couple of weeks, but that does not stop the Telegraph from suggesting Real Madrid, Bayern Munich and Barcelona are all keeping an eye on the situation.
With Mancini's future at the ailing Premier League champions far from certain itself, it may be he and not Kompany that is seeking new pastures in the summer.
However, successive failures in the Champions League and disharmony within the City squad may convince the 26-year-old defender that it's time to end his five year stay at the Etihad Stadium.
Certainly there would be no harm in Barcelona making enquiries about the former Anderlecht and Hamburg star, and although the cash-rich club would not be willing to sell, nobody wants to keep hold of a player who doesn't want to be there.
Barcelona will definitely be in the hunt for a top class central defender during preseason with Carles Puyol on the wane and only a couple of young and relatively untried academy graduates to choose from behind him.
There are few better defenders in world football than Kompany, and his proven Premier League and European pedigree means he's a fail-safe option for any side.
Kompany is also noted as a gentleman of the game and his conduct for City has often reflected well on a club who have had their fair share on internal strife.
The Belgian is a fan favourite around the Blue half of Manchester and has been a figurehead during City's rise to success.
But his position does seem rather more insecure than it did this time 12 months ago, and if Mancini remains at the club, a concrete offer from Barcelona could well tempt him to cut his ties.
What do you think? Should Barcelona test Kompany and Manchester City's resolve with a bid this summer, and if not, which defender do you think the Catalans should make a move for?
For more, follow me on Twitter @bainesyDiego10
Like the new article format? Send us feedback!