Indiana entered its Sweet 16 matchup against Syracuse not only as a favorite in the game but also a favorite to win its first national title since 1987.
Then, Syracuse jumped out to a quick 11-3 lead and never looked back, comfortably giving Indiana a defeat in the Sweet 16 for the second consecutive year.
This one had to sting for Indiana. The Hoosiers started the season ranked No. 1 in the country, and everything seemed to be in place to completely cap off the program’s rebirth under fifth-year head coach Tom Crean.
While this loss certainly was painful, how does it stack up to some of the other tough defeats in the history of Indiana basketball?
Here is a countdown of Indiana’s all-time worst defeats in the NCAA tournament.