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Sunderland vs. Manchester United
The Red Devils have an FA Cup match with Chelsea on Monday, which means Sir Alex Ferguson may choose to shake his lineup for this clash. Still, he won't go completely overboard knowing United doesn't want to give City even a glimmer of hope in the title chase.
Prediction: 2-0 Manchester United
Arsenal vs. Reading
Arsenal understands their margin for error in order to qualify for the Champions League is extremely small. That means home matches against clubs currently sitting in the relegation zone are must-wins at this point in the campaign. The Gunners will deliver.
Prediction: 3-1 Arsenal
Manchester City vs. Newcastle United
City should be able to take advantage of a shaky Newcastle back line that ranks near the bottom of the Premier League in goals allowed. The second-place squad hopes United slips up before their upcoming clash to open the door for a late run.
Prediction: 3-0 Manchester City
Southampton vs. Chelsea
Southampton was able to fight back from a 2-0 deficit to earn a draw in the first league match between the two sides this season. The Blues probably won't be as forgiving this time around as they try to put some distance between themselves and Tottenham.
Prediction: 2-0 Chelsea
Swansea City vs. Tottenham Hotspur
Speaking of the Spurs, it will be interesting to see if Gareth Bale and Co. can get back on track after their recent skid. Now that teams are focusing their defensive efforts on Bale, Tottenham needs other players like Clint Dempsey to step up.
Prediction: 2-1 Tottenham
West Ham United vs. West Bromwich Albion
Even though West Brom have put together a strong campaign, in large part due to the emergence of Romelu Lukaku, they haven't been nearly as effective on the road. That should allow West Ham to earn at least a point as they look to avoid a relegation battle.
Wigan Athletic vs. Norwich City
Wigan have their sights set on Aston Villa with a match in hand and three points away from safety. If they want to catch Villa, or another club near the bottom of the table, they can't afford to drop points in their remaining winnable home matches.
Prediction: 2-1 Wigan
Everton vs. Stoke City
Everton have quietly gotten back in contention for Europe after a slide dropped them out of the picture for awhile. As always, the Toffees will need to be patent as they attempt to break down the strong Stoke back line, but they should be able to earn all three points.
Prediction: 1-0 Everton