The last time that Duke lost as a favorite, the Blue Devils were victimized by the Maryland Terrapins.
With a point spread of 13 points as of midday Friday, do Blue Devil fans and bettors remember that cautionary tale or blindly back their team?
The ACC tournament quarterfinals begin Friday in Greensboro, N.C., and the Duke vs. Maryland matchup carries extra intrigue.
Maryland managed to split its two games with Duke this season, losing in Durham, N.C. 84-64 but pulling the aforementioned 83-81 upset in College Park, Md.
All four higher-seeded teams advanced Thursday. Boston College, which began early Friday against heavily favored Miami, overcame a 15-0 deficit out of the blocks to roar back and beat Georgia Tech 84-64.
Then fifth-seeded North Carolina State topped Virginia Tech 80-63; Maryland beat Wake Forest 75-62; and last night defending tournament champion Florida State hung on to defeat Clemson 73-69.
Later Friday, the Wolfpack takes on Virginia (2 p.m. ET, ESPN2). Then the Terps challenge second-seeded Duke (7 p.m. ET, ESPN2). Finally, to cap off the day, the Seminoles go against third-seeded North Carolina (9 p.m. ET, ESPN2).
NC State was favored by a point-and-a-half over the Cavaliers. In the only previous meeting this season between Virginia and North Carolina State, the Wahoos rallied in the second half for a 58-55 victory.
And Carolina swept two games from FSU during the regular season, winning 77-72 in Tallahassee, Fla. and 79-58 in Chapel Hill, N.C.
On the updated ACC tournament betting board at OddsShark.com, Duke is listed as a minus-250 favorite, followed by Miami at plus-250.
Behind them, dangerous North Carolina was at plus-350, North Carolina State at plus-650 and Virginia at plus-1,200.
Maryland was one of the bigger longshots at plus-1,500, along with Florida State at plus-2,000 and Boston College at plus-5,000.