The weekend matches are almost upon us once more around the world of football, and we take our usual look around the game at those who are suffering or recovering from injuries.
European football can take its toll just as much as the domestic game, and a couple of players picked up new injuries during the week.
Here's the complete roundup of the biggest names in the game and their progress during their recoveries.
A number of Premier League players are hoping to make their return to action for their clubs this weekend.
Liverpool goalkeeper Pepe Reina has recovered from the calf injury that saw him miss the 3-2 win over Tottenham and should play against Southampton. Martin Kelly is back in light training after an ACL injury, but may not play again this season.
Down the road in Manchester, Phil Jones hopes to make his comeback for United this weekend, while rivals City are hopeful that defender Vincent Kompany and striker Sergio Aguero will both be fit too.
Strikers Shane Long (Reading) and Emmanuel Adebayor (Tottenham) hope to return by the weekend, though the Togolese forward will likely miss Spurs' Europa League game on Thursday.
Norwich City are waiting on the return to full fitness of John Ruddy and Alex Tettey, both of whom are close to action.
Arsenal are also without key midfielder Jack Wilshere, who will miss at least three weeks.
Over in the German Bundesliga, we have several big-name players still suffering with knocks and strains.
Borussia Dortmund defender Mats Hummels has recovered from a recent illness but has now suffered ankle ligament damage and may miss the next few weeks.
League leaders Bayern Munich are without defender Holger Badstuber until the end of the season, but they have the rest of the squad fighting fit as they challenge on three fronts for trophies.
Wolfsburg's Ivan Perisic (knee ligament), Werder Bremen's Clemens Fritz (fractured cheekbone) and Greuther Furth's Djiby Fall (knee ligament) are all still out of action but hope to return by the end of this month to play a part in the end-of-season run-in.
Over to Spain's La Liga now and the top flight with the most representatives left in the Champions League.
The big news for Real Madrid is the return to light training of goalkeeper Iker Casillas, who is recovering from a hand fracture.
Granada's Dani Benitez, out with a hernia, is also closing in on a return to first-team football.
Joao Victor of Mallorca and Ivan Obradovic of Real Zaragoza are both getting closer to returning from ACL ruptures, and they may be required to jump back in as soon as possible with both sides desperately trying to avoid the drop to the Segunda Division.
Sevilla are without midfield duo Piotr Trochowski and Jose Campana until the end of the season.
Now for our regular stop over in Italy's Serie A, where we are awaiting the return of several big names before the end of the season.
Fiorentina's new forward signing, Giuseppe Rossi, has almost completed his recovery from the cruciate ligament injury that has plagued him for two seasons. He should be ready to make his debut either at the end of the month or the beginning of April.
Roma, still chasing a Europa League place, are waiting on three key players to recover. Mattia Destro should be back within the next week or two, while Miralem Pjanic (ankle) and Leandro Castan are not due to return until early April.
Inter Milan left-back Yuto Nagatomo and Juventus' Paolo de Ceglie should be back for the weekend.
Later in the season, Palermo's Abel Hernandez (ACL), Lazio's Miroslav Klose (knee ligament) and Cristian Brocchi (broken foot) and AC Milan's Nigel de Jong (Achilles) may all make returns from long-term injuries.
Injury data taken from transfermarkt.co.uk