Milan eagerly await what Massimiliano Allegri described as "the strongest team in the world" to Milan Chanel (h/t Football Italia).
Barcelona are coming to town and are red hot favourites despite playing in the Rossoneri's back yard.
The Stadio Giuseppe Meazza will play host to the third meeting between two of Europe's most illustrious clubs for the third time in 18 months.
The last result at the San Siro was a 0-0 in the first leg of their knockout tie having played each other in the group stages earlier, the Blaugrana triumphing 3-2 on that occasion.
Here is what has been said in the Italian media in the build up to this massive game.