The Premier League takes a backseat this weekend, as most of the top clubs are on FA Cup duty.
After a midweek fixture list that saw the return of the Champions League, there are some clubs who will need to step up to the plate in the FA Cup.
Manchester United haven't won the cup since 2004, and Sir Alex Ferguson will want success this time around.
Wayne Rooney scored in their fourth round tie with Fulham as United eased into the fifth round with a 4-1 win.
He'll be a key figure this weekend if United are to overcome Reading and progress to the quarter finals.
Chelsea are another Premier League side who will be gunning for glory because, to be quite honest, the Premier League title isn't coming to Stamford Bridge.
They struggled in their first encounter with Brentford, who they play again this Sunday to try to get to the next round.
Given their current inconsistent form, Brentford will go to Stamford Bridge with the belief that they can get a result, and if that happens, surely Rafael Benitez's position will be untenable?
There are some interesting matches this weekend, so without any further ado, let's run through the six fixtures to keep an eye on.