The UEFA Champions League tie was finely poised despite a third-minute goal from Alessandro Matri that initially rocked Celtic Park, pitting an expansive and attack-minded Bhoys side against a well-drilled Italian outfit.
Antonio Conte's troops stood up to absolutely everything the Scottish champions could muster. Despite some fine crossing and pressure from full-backs Emilio Izaguirre and Mikael Lustig, the Old Lady kept a vital clean sheet away from home.
Despite losing, Celtic looked unfazed. They chased every second ball, closed down Andrea Pirlo with gusto and looked a threat in behind Juventus' full-backs.
It was simply the timing of Juve's second that killed them.
Breaking from a corner kick, Conte's side burst down the left-hand side through Federico Peluso and the defender paused to take stock of things.
His threaded ball into Alessandro Matri's feet was flicked to the onrushing Claudio Marchisio, who beat his marker, jinked inside and finished past Fraser Forster with consummate ease.
The Italian, who has made his name as one of the most explosive box-to-box midfielders in world football, has been a reliable figure for the Bianconeri all season long and rivals the very best when it comes to proving and stretching the left-hand side.
Just minutes later, Efe Ambrose was robbed in possession and a combination of Marchisio and Mirko Vucinic made it 3-0.
Can Celtic mount a historic comeback at the Juventus Stadium in three weeks time?