Thiago had the first chance for el blaugrana when a nice long pass from Carles Puyol found Thiago, but the kid couldn't get the lob shot right as Osasuna goalkeeper Andres Fernandez stopped the shot.
Messi got his goal in the 11th minute when Xavi's smooth pass just outside the box found Leo inside the box. Leo then toyed with Fernandez, as the goalkeeper was helpless in stopping Messi from getting the goal.
Messi is now the only player in the history of La Liga to score in 11 straight games.
Osasuna tied it up in the 24th minute when a Marc Beltran low cross was deflected off a defender and landed at the feet of Raouk Loe, who blasted the ball from the top of the box and into the back of the net for the equalizer.
Just three minutes later, a handball was called inside the box on Alejandro Arribas, who picked up his second yellow card. This led to Messi slamming the spot kick for the 2-1 lead. That goal was Leo's 200th Liga goal in his stellar career.
A bad call by the referee took away a Barcelona goal in the 36th minute. Messi's header hit the post in the 38th minute.
The third Barcelona goal came from Pedro. Another terrific Xavi pass found Dani Alves, who stayed onside, then toyed with the goalkeeper, who essentially had to face a three-on-one (Alves, Pedro, Messi). Dani then passed it to Pedro, who faked out a defender and put it in for the 3-1 lead.
In the second half, Messi grabbed his third goal in the 56th minute. A great pass from David Villa set up Leo, who faked a defender—and the goalkeeper—and slid the ball in for his hat-trick.
Just a minute later, Villa found Adriano, whose pass found Messi for Leo's fourth goal of the night. Simply amazing.
Alexis Sanchez's shot just went wide in the 75th minute. Messi's attempt at a fifth goal was blocked by Osasuna in the 78th minute.
David Villa had a wide-open look in stoppage time, but Fernandez made a nice stop to prevent any further damage.
FINAL: FC Barcelona 5 - 1 Osasuna
Once again, Lionel Messi tops Cristiano Ronaldo, as Leo's four-goal night topped Ronaldo's three-goal night against Getafe earlier on Sunday.
Let's talk about my four most important things from this game "From The Mind of Xoel," as FC Barcelona dominated Osasuna 5-1 at the Camp Nou on Sunday.