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I don't think we'll see this much against San Francisco.
Matt Ryan threw three touchdowns and got a monkey off his back against Seattle, but it's hard to completely trust him.
In 17 games this year, he has thrown 16 interceptions, while making a lot of poor throws and making some bad decisions. He was intercepted twice against Seattle, and on the first one, he failed to pick up a blitz and rushed a throw instead of taking a sack.
Ryan had a lot of high throws as well, and his throws weren't great. In my eyes, he isn't elite, and against a tough pass rush, he will struggle. Ryan has thrown 13 interceptions in nine games against top-18 defenses, and he has been picked off 10 times in seven games against top-12 defenses.
The 49ers have the third-best defense in the league, and their pass defense is fourth in the league. Justin Smith and Aldon Smith are great pass rushers, and they'll give Ryan a hard time. If they can get in his head early and make him force some throws, he'll struggle, especially with Dashon Goldson, Donte Whitner and others roaming the secondary and Patrick Willis and NaVorro Bowman covering the underneath routes.
If Ryan is harassed early and forced to come back, he will have trouble, and will probably have to do it without much help from the run game (the 49ers have the fourth-best run defense in the league). Ryan will probably be overwhelmed, and chances are that he will make a mistake.
And if he does, San Francisco will be in Super Bowl XLVII.