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Brandon Browner and Richard Sherman will be matched up man-to-man with Atlanta's big-name receivers, Julio Jones and Roddy White.
Tony Gonzalez is likely to garner the attention of either Earl Thomas or Kam Chancellor. Each of those matchups potentially favor Seattle.
The result could mean a big game from Atlanta's third wide receiver, Harry Douglas.
Douglas was one of the better third receiver options in the league in 2012, hauling in 38 receptions for 396 yards and a touchdown.
He didn't make as many big plays as he has in the past. That's partially because the second-year Jones took the next step in his progression as an NFL receiver. Few defenses possessed the man power to slow the trio of Jones, White and Gonzalez. Thus, Douglas was not needed as much as in prior seasons.
As already established, Seattle is one of the few teams capable of containing that superstar trio.
Douglas must have one of his better games in this contest if Atlanta is going to emerge victorious and win its first playoff game in the Mike Smith/Matt Ryan era.