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NFL Week 16 Predictions: Latest Odds and Picks Against the Spread

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NFL Week 16 Predictions: Latest Odds and Picks Against the Spread
Brian Bahr/Getty Images

With no Thursday night game in place for the first time all season, bettors will get some extra time to analyze their picks against the spread for Week 16 of the NFL season. 

Like every week in this space, we'll use the betting trends, series histories and recent performances to help guide your NFL betting adventure. No method has proven to be 100 percent correct, but using the statistical data and trends almost always beats picking games using your first gut reaction. 

In the following slides, we'll present the important betting data and our picks against the spread for Week 16 of the NFL season. 

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