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Wigan Athletic vs. Arsenal
Arsenal have been plagued by inconsistency, but the positive strides made by players like Lukas Podolski and Olivier Giroud should lead to a second-half surge. They should be able to get a head start against a struggling Wigan side.
Prediction: 2-1 Arsenal
Manchester City vs. Reading
Even though United have built a six-point lead, City are still firmly in the title chase. They can't afford to drop any points against opponents like Reading, though. These are the matches City must win handily to ensure they keep pace.
Prediction: 3-0 Manchester City
Newcastle United vs. Queens Park Rangers
This match features two clubs that are desperate to get out of their current positions. Newcastle are just two points clear of the relegation zone after a fifth-place finish last season. QPR have shown signs of life after a brutal start, but are still stuck near the bottom. Every point counts.
Southampton vs. Sunderland
Another matchup of teams on the brink of the relegation zone. These matches don't get much attention during the week, but they are crucial for both sides, even in December. Southampton have been much better at home—a trend that should continue on Saturday.
Prediction: 1-0 Southampton
Tottenham Hotspur vs. Stoke City
It's hard not to like what Tottenham have accomplished lately. They played far from their best against Swansea over the weekend and still managed to earn all three points. Creating chances against Stoke will be a challenge, but one tally should be enough.
Prediction: 1-0 Tottenham
West Bromwich Albion vs. Norwich City
West Brom are in a major scoring drought. They haven't found the net in any of their past three matches, including a scoreless draw with West Ham on Sunday. A shaky Norwich back line should provide some relief for the Baggies.
Prediction: 2-1 West Brom
West Ham United vs. Everton
Everton already have nine draws, tied for the most in the Premier League. In order to remain in contention for a top-four spot, the Toffees must start turning one point into three against opponents like West Ham. It's hard to have confidence they will, though.
Liverpool vs. Fulham
Any momentum Liverpool had built up in recent weeks was eliminated during their loss to Aston Villa. The Reds couldn't capitalize on early chances, and Villa took advantage. Fulham haven't been in top form, either, making this match a toss-up.