An 11 seed, two 12 seeds, and a 13 seed all advanced to the second round with major upsets.
Dayton, an 11th seed, got its first tourney win in 19 years by knocking off West Virginia; the Flyers kept WVU off-balance on offense all day long as they rolled to an eight-point win
Arizona was thought to be the last team in the tournament and they showed that they definitely belong by knocking off the fifth-seeded Utes of Utah. The Wildcats shot 54 percent from the field and outscored the Utes by 20 in the paint as they cruised to a 13-point victory.
Wisconsin outlasted Florida State 61-59 in one of two overtime games of the day. Trevon Hughes made an outstanding move to get to the basket and hit the game winning shot with just two seconds left. Toney Douglas for the Seminoles led all scorers with 26 points.
Cleveland State rushed out to a 29-12 lead early in the first half and and Wake Forest never drew closer than seven the rest of the way as the fourth seed was blown out 84-69. The Vikings, playing in only their second NCAA tourney, pushed their record to 2-0 in the first round with the victory over the Demon Deacons.
Other notable action included:
Siena knocked off Ohio State in two overtimes, in one of the better games of the day. Ronald Moore hit the game winning three with just four seconds left to advance the Saints. He also forced the second overtime with a three from almost the same spot.
Louisville only led by two at halftime, but used an early run in the second half to put away Morehead State 74-54.
Michigan State rolled past Robert Morris 77-62 in an easy first-round win.
Oklahoma State got a three-point play from Byron Eaton with just eight seconds left to advance past the Tennessee Volunteers.
Marquette squeaked by Utah State 58-57 in the first round. Lazar Hayward had a game-high 26 points for the Eagles.
Kansas got a career-high 32 points from Sherron Collins to advance past North Dakota State. The Bisons, playing in their first tourney, ever got one of the best performances of the tournament as Ben Woodside scored 37 points in a losing effort.
Syracuse had no problem with Stephen F. Austin, as they won easily 59-44. The Lumberjacks, playing in their first tournament ever, might have had some nerves going as they only 24 percent from the floor in the losing effort.
Pittsburgh only led 16th-seed East Tennessee State by four with 3:30 left to play, but the Panthers came through down the stretch and went on to a 72-62 win to avoid the shocker. This was another close effort for a 16 seed, but still, a 16 seed has never beaten a 1.
Missouri had no problem with the Big Red from Cornell, as they won 78-59 to advance to the second round. The Tigers got a game-high 23 points from Leo Lyons.
Arizona State shot 51 percent from the floor as they beat Temple 66-57 and have now won 25 games for the first time since 1975. Dionte Christmas of Temple led all scorers with 29 points.
USC beat Boston College 72-55 thanks to a perfect night from the floor from Taj Gibson. He was 10-of-10 from the floor with 24 points.
Xavier thumped Portland State by a score of 77-59, Xavier outscored Portland State by 20 points in the paint.
The second round just got under way, with Villanova and UCLA fighting for a berth in the sweet 16.