Ahmad Brooks and Donte Whitner returned interceptions for touchdowns, the 49ers sacked Drew Brees five times, and San Francisco ended the New Orleans Saints' three-game winning streak, 31-21 on Sunday. Colin Kaepernick was solid in his second-career start while Alex Smith, deemed healthy enough to suit up, watched from the sideline. Kaepernick passed for 231 yards, including a short touchdown to Frank Gore. He also ran for a 7-yard score. He threw his first career interception, but it was inconsequential.