Three games down, two 100-yard rushing days in the books.
Houston's Arian Foster (20 carries for 102 yards and two touchdowns) and Washington's Alfred Morris (24 carries for 113 yards and a touchdown) bought home bonus points for fantasy squads on Thanksgiving, with New England's Stevan Ridley (21 carries for 97 yards and a touchdown) falling three yards short.
But they won't be the only running backs to finish Week 12 with triple-digit rushing performances, leading fantasy teams to victory in crucial Week 12 games.
Let's take a look at the other backs who are locks to break the century mark.
Doug Martin, Tampa Bay Buccaneers
The Falcons' defense has held only two opponents to fewer than 100 yards, and they won't be able to keep Martin from adding to that total.
Tampa Bay's dynamic rookie has picked up at least 100 yards on the ground in three of his past four games, including 24 carries for 138 yards against the Carolina Panthers last week.
Expect more big-time production from Martin against the Falcons, with at least 125 yards rushing and a touchdown by the time the final whistle blows.
Frank Gore, San Francisco 49ers
Whether it's Colin Kaepernick or Alex Smith under center for the 49ers, San Francisco is going to give the New Orleans Saints a heavy dose of Frank Gore. Not only will running the ball eat clock and keep Drew Brees on the sidelines, but nobody in the NFL runs the ball as well as the 49ers, who average 165 yards per game.
Frank Gore hasn't eclipsed 100 yards since Week 7, when he picked up 131 yards on 16 carries against the Seattle Seahawks. He'll get back over 100 yards on Sunday against a Saints defense that allows 157 rushing yards per game to opposing running backs.
Chris Johnson, Tennessee Titans
Chris Johnson is back, having rushed for at least 100 yards in three of his last four games—and he finished with 99 yards in the other.
Coming off of a bye, Johnson and the Titans take on a Jacksonville Jaguars defense that is awful against the run, allowing the third-most fantasy points per game to running backs, according to fftoolbox.com—and one of five defenses to allow at least 20 points per game to opposing running backs in standard-scoring ESPN leagues.
This could be another game like Johnson had against the Buffalo Bills in Week 7, when he carried the ball 18 times for 195 yards and two touchdowns.
Marshawn Lynch, Seattle Seahawks
Miami's stellar run defense has disappeared over the past month, with the Dolphins surrendering 110 rushing yards per game during that time, including 126 to Tennessee's Chris Johnson two weeks ago and 91 to Buffalo's C.J. Spiller last week.
Marshawn Lynch, with at least 100 yards rushing in each of his past four games, will make it five in a row against the Dolphins, hitting triple digits and finding the end zone for Seattle.
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