With a plethora of Week 13 games already completed on Thursday and Friday, bettors across the nation will have far fewer games to pick from than a usual Saturday.
Nevertheless, the lack of games doesn't mean a lack of intrigue. BCS bowl matchups and bitter in-state rivalries will be decided, as the picture across the nation will finally start to clear up.
With so many top-tier games on the slate, you won't want to miss a minute of the action—or a solid bet to make.
For that reason, here's a look at all the latest spread information for the remaining Week 13 games, along with a look at a few of the best wagers you can make.
(All odds are courtesy of Bovada.)
Lock of the Week
Connecticut Huskies at No. 20 Louisville Cardinals
Over/Under: 46, Spread: Louisville (-11.5)
The last time we the Louisville Cardinals, their undefeated dream was ending, as they were being taken to the woodshed by an unranked Syracuse squad.
Nonetheless, Louisville has had a week to think about that loss and should come out on fire. Quarterback Teddy Bridgewater has been marvelous all season, and the two-headed rushing attack of Senorise Perry and Jeremy Wright is one of the most underrated duos in the nation.
On the other side of the field, things started bad and have only gotten worse for Connecticut in 2012. The Huskies are just 4-6 on the season, including a 1-4 mark in a weak Big East conference, and are losers of four of their past five games.
Connecticut especially struggles on offense, scoring just 17.3 points per game, good for 121st in the FBS.
With the high-powered Cardinals in store for Saturday, it seems impossible that the Huskies can keep up.
No. 1 Notre Dame Fighting Irish at USC Trojans
Over/Under: 46, Spread: USC (+5)
Call it a premonition or whatever you like, but I've had USC tabbed to win this game since last week, and my stance hasn't changed.
Matt Barkley's injury will obviously linger large here. Replacement Max Wittek is a completely unproven commodity and will get his first career start on Saturday. Still, he was one of the top recruits in his class for a reason and certainly isn't lacking in confidence after guaranteeing a victory this week (per USA Today).
While linebacker Manti Te'o and the Notre Dame defense have been phenomenal all season, the Irish have not seen athletes on the outside like Robert Woods and Marqise Lee on the outside. Couple those receivers with a strong running game, and you have a recipe for the first disappointing defensive performance of 2012 from Notre Dame.
If Wittek performs, the Trojans will come away with a potentially job-saving upset for head coach Lane Kiffin.
Underdog That'll Cover the Spread
Auburn Tigers at No. 2 Alabama Crimson Tide
Over/Under: 47, Spread: Alabama (-33.5)
Clearly, Auburn has an igloo's shot in the Amazon of actually beating Alabama on Saturday. The Tide has more talent in every facet of the game and the nation's best head coach leading the charge.
Nevertheless, the Tigers getting nearly five touchdowns against their biggest rival is too much to pass up.
Auburn comes into Saturday's matchup with an 0-7 record in the conference and looking to avoid its worst full-season record since a 2-8 mark back in 1952.
Tigers head coach Gene Chizik is essentially coaching for his job on Saturday as well, so expect to see every trick he has remaining in the bag to make this game close. It won't work, and the game will still be a blowout, but just not of the 34-plus point proportion.
No. 19 Michigan Wolverines at Ohio State Buckeyes
Over/Under: 54, Spread: Ohio State (-5)
Georgia Tech Yellow Jackets at No. 3 Georgia Bulldogs
Over/Under: 64, Spread: Georgia (-14)
No. 18 Rutgers Scarlet Knights at Pittsburgh Panthers
Over/Under: 44, Spread: Pittsburgh (-1)
No. 21 Oklahoma State Cowboys at No. 13 Oklahoma Sooners
Over/Under: 71, Spread: Oklahoma (-6.5)
No. 5 Oregon Ducks at No. 15 Oregon State Beavers
Over/Under: 66, Spread: Oregon State (+10)
No. 4 Florida Gators at No. 10 Florida State Seminoles
Over/Under: 44, Spread: Florida State (-7)
No. 8 Stanford Cardinal at No. 17 UCLA Bruins
Over/Under: 51, Spread: UCLA (+3)
Missouri Tigers at No. 9 Texas A&M Aggies
Over/Under: OFF, Spread: OFF
No. 12 South Carolina Gamecocks at No. 11 Clemson Tigers
Over/Under: 62, Spread: Clemson (-3)