With seven divisional showdowns and playoff races heating up, we're bound for a ton of wildly entertaining games in Week 11.
The Indianapolis Colts and New England Patriots rivalry takes on a new look with Andrew Luck under center.
The Detroit Lions and Green Bay Packers square off in a crucial NFC North battle, and Peyton Manning's Denver Broncos look to increase their lead in the AFC West.
Oh yeah, and Drew Brees will attempt to lead his Saints to their fifth win in six games.
Here are predictions for all of Week 11's action.