Florida State is ranked No. 1 in the country in total defense and No. 3 in scoring defense. On Sept. 22 in Tallhassee, Clemson scored 37 points and had 426 total yards against the Seminoles. That game exemplifies the challenge of defending Clemson's explosive spread offense that features potential All-ACC players at quarterback, running back, receiver and tight end.
Streeter Lecka/Getty Images