The Indianapolis Colts and New England Patriots have given us roughly a decade of Manning vs. Brady. Now, we get to see the start of Luck vs. Brady—for the next couple of years, anyway.
Brady and the Patriots have been far from the dominating team we've grown accustomed to over the years, but they match up well with the Colts, save for one area—in the secondary. Andrew Luck and the Colts have just enough on offense to make things interesting.
Luck in particular is a nightmare for the Patriots. He is able to keep his eyes upfield in the face of the rush, is incredibly elusive and makes plays even when guys are hanging off him.
Aquib Talib should get his first start for the Patriots since they traded for him, and you have to expect Belichick will have him shadow Reggie Wayne wherever he goes on the field.
In the video above, we take a look at the biggest matchups and give our predictions for the game. Let us know in the comments below what you'll be watching for and who you have winning the game.