Week 10's most pivotal matchup will be played Sunday afternoon in Philadelphia, where the Eagles (3-5) will play host to their NFC East rival, the Dallas Cowboys (3-5).
Neither team can afford a loss, and that only adds to the intrigue, considering the amount of fantasy studs who will take center stage in this showdown. Fans will be looking for Tony Romo, Michael Vick and LeSean McCoy to play well.
But what about the game-breakers?
Let's highlight a trio of players set to break out in Sunday's must-see NFC East clash.
Felix Jones, RB
The Philadelphia Eagles surrendered 140 rushing yards to the New Orleans Saints, who entered Week 9 as the worst rushing offense in the NFL. Cowboys fans and fantasy owners can be confident that DeMarco Murray's backup, Felix Jones, will thrive on the ground in Week 10.
Jones has carried the ball 55 times for Dallas since Week 6, averaging just over 3.5 yards per carry during that time. The good news is that he has two rushing touchdowns over the past four weeks and an additional 113 receiving yards.
If the league's worst running team can average 5.6 yards per carry against Philly's front seven, then why can't Jones run for 100 yards on 20 carries this weekend?
There's no reason Jones shouldn't find daylight easy to come by on Sunday.
DeSean Jackson, WR
Sure, Dallas boasts one of the best secondaries in football this season. But with all the attention the Cowboys' last line of defense will have to pay Philadelphia running back LeSean McCoy on Sunday, play-making wideout DeSean Jackson is a lock to break out.
More positive news for Jackson owners: The Eagles' No. 1 receiving option recorded his second 100-yard receiving game and second receiving touchdown of the season last week against New Orleans.
The fifth-year player out of Cal is still averaging nearly 17 yards per reception in 2012, which makes him a big-play threat and an awesome fantasy starter this weekend. If Jackson doesn't record another 100-yard receiving day, he'll definitely make up for it with a touchdown.
Miles Austin, WR
The explosion of Cowboys tight end Jason Witten has caused star wideout Miles Austin to fly under the radar for the most part in 2012, but that should change on Sunday afternoon.
Philly would be foolish to let Witten, who has 25 catches in the last two games, roam up the field uncovered. Expect Andy Reid and the Eagles to shut down the veteran target at all costs in Week 10, opening the field for Dallas' wide receivers.
Austin has been targeted by Tony Romo 25 times over the past two games, recording 16 receptions for 209 yards. The only thing Austin hasn't produced recently have been touchdowns. You have to go all the way back to Week 7 at Carolina to find the last time Austin scored. He has four in eight games in 2012.
The Eagles have given up 12 touchdowns through the air in eight games this season, which means that the Cowboys will likely find some scoring in the passing game this weekend.
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