Louisville - 26 Syracuse - 45 Final
The Louisville Cardinals are undefeated no more.
Ryan Nassib and the Syracuse Orange dominated the Cardinals, pulling off the big upset at the Carrier Dome.
The Cardinals were only three wins away from finishing off an undefeated season, but it was not to be against the Orange.
Charlie Strong's team is going to have to try and regroup, and find a way to knock of Rutgers in their final game of the season if they hope to revive dreams of a BCS game.
Check here for what we learned from Louisville's loss to Syracuse.