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In the boldest prediction of the week, the Buffalo Bills will upset the New England Patriots.
The Bills are double-digit underdogs and sitting in the basement of the AFC East. With all of those obstacles in front of this team, it has yet to give up. The Bills are only two games out of first in the division and a win against the Patriots would go a long way to get them back in the race.
They upset the Patriots last year and are confident they can play with Tom Brady this Sunday.
Unlike other teams, the Patriots are a bad bet after a bye week. The Patriots are 1-3-1 against the spread (ATS) in their last five games following a bye week and 1-4 ATS in their last five home games.
The Bills had a lead (21-7) in the first meeting, but they could not hold on. The Bills' defense has improved since then and looked much better against the Houston Texans a week ago.
It’s the Patriots' defense that has the problems. The Patriots will have a big mismatch problem against CJ Spiller who has beaten this defense in the past.
The Bills are a steal at +11 and will pull off the upset of the week.
Prediction: Bills 38, Patriots 35
James Brown is a B/R featured columnist and can be followed on Twitter. Feel free to contact James at email@example.com. He also is a contributor at Bookie Blitz, a sports picks website.