Injuries are a regular part of college football life that every team has to deal with at some point.
That doesn't make them any easier to handle when they happen, nor have less of an impact on the games.
This season has had its share of tough injuries, with several key players suffering season-ending injuries.
The fact is that not every injury has a huge impact on the BCS picture.
The injuries on this list are the top candidates to make some sort of difference in the competition to reach the pinnacle of the postseason.
Sutton missed the Sun Devils game against UCLA with a knee injury suffered the previous week against Oregon.
While he played last week against Oregon State, Sutton's knee is not quite back to 100 percent yet and could be a problem in the upcoming weeks for ASU.
Sutton has already registered 9.5 sacks on the year in spite of missing one game, and continues to be a force up front.
The Sun Devils still have a slim shot at finishing atop the South Division of the Pac-12, if a few things go their way, and having Sutton at anything less than full health would be severely damaging to this team's chances of finishing strong.
Clemson is tied with Florida State atop the ACC Atlantic division.
The Tigers are on the wrong side of the tiebreaker with the Seminoles after their loss to the 'Noles earlier in the season.
With tough games coming up against North Carolina State and South Carolina, Clemson needs to buckle down and finish strong.
Without Darius Robinson, the Clemson secondary is even more porous than it already was and will have a difficult time keeping teams from racking up big yards.
Robinson will not be back this season after suffering a fractured ankle and broken leg against Virginia Tech.
The Gamecocks' chances of winning the SEC East were slim to none after two consecutive losses to LSU and Florida.
They got even slimmer last week when running back Marcus Lattimore blew up his knee for the second consecutive season.
Lattimore had scored 11 rushing touchdowns on the season and was on pace to break the 1,000-yard mark for the year.
His loss is a serious blow to an offense that needs some consistency, and without him, the chances of Steve Spurrier's team heading to a BCS game went from slim to none.
While nobody would mistake Wisconsin quarterback Joel Stave for Johnny Manziel, there is some definite potential there.
Stave gained over 1,100 yards through seven games for the Badgers before suffering a season-ending broken collarbone.
While the Badgers are not world-beaters this year, they are still the prohibitive favorite to represent the Big Ten's Leaders division in the conference championship game due to the postseason bans on both Ohio State and Penn State.
With Stave out, they must turn to Curt Phillips, who hasn't seen time on the field since 2010, or Danny O'Brien, they starter who lost his job to Stave.
So even if the Badgers do make it to the conference title game, they will make a bid for their third consecutive trip to the Rose Bowl without their best option at quarterback.
Louisville is sitting pretty at 9-0 on the season, and with no difficult games ahead of it until the season-ending meeting with Rutgers, we could be looking at an undefeated Big East champion.
In their last game, Mauldin suffered a sprained knee and is expected to miss a few games.
Mauldin is the team's sack leader, with 4.5 on the season.
If he does not recover to find his way onto the field for the season-closing game against Rutgers, the Cardinals are going to have problem.
Florida State is not exactly bereft of talent with Thompson out for the season due to to a knee injury.
James Wilder, Jr. is averaging almost six yards per carry and has proven to be an apt replacement for Thompson.
But this injury is going to be an issue in the BCS race for a different reason.
Thompson's story was an inspiring one, as he suffered two broken vertebrae last season and yet came back from that injury to not only walk again, but lead the Seminoles in rushing this season.
The motivation of winning the conference and finding the way into a BCS game will be huge for this team, but the added component of wanting to win and win big for a teammate may push the Seminoles into playing at a whole new level.
Not good news for the rest of the ACC.
Collin Klein is the Heisman favorite, one of the most talked about players this college football season and the catalyst for the K-State offense.
Klein's injury and the status of said injury has created a bit of a controversy around college football's policy about revealing the status of injuries.
While we are not sure what exactly the extent of Klein's injury might be, if he is going to be limited or the chances that he will be re-injured are increased and he is forced to pull back a bit, K-State might be in trouble.
The Big 12 is a minefield to navigate even at full strength.
With a starting quarterback out, things might get rough.
The Irish are en route to an undefeated season and possible bid in the BCS title game.
Boston College, Wake Forest and USC stand in the way of Brian Kelly's team and a perfect year.
BC and Wake are not huge concerns, as Notre Dame should win, and win big against both of those squads.
The problem comes against USC.
The Irish are missing three players—Lo Wood, Jamoris Slaughter and Austin Collinsworth—from the secondary.
Against USC and its incredible passing game, this is going to be a major problem.