This week on Bleacher Report's Behind the Mic, Cris Collinsworth breaks down the three biggest locks of Week 10. With massive games on the horizon, there's no telling what the outcome will be, but Collinsworth is sure these picks are excellent bets.

Who will win between the Buffalo Bills and the Tom Brady-led New England Patriots? Can the Kansas City Chiefs stop their slide against the Steelers and steal one in Pittsburgh? Will the Seattle Seahawks continue to dominate on their home turf when Mark Sanchez and Tim Tebow come to town?

Check out Collinsworth's picks now and stay tuned for more Behind the Mic.