NFL Week 10 Picks: Predicting Every Game Against the Spread

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NFL Week 10 Picks: Predicting Every Game Against the Spread
Jamie McDonald/Getty Images

Week 10 is a critical point in the NFL season for gamblers. Lines are starting to get tight, but there is still value to be found by wagering against certain teams on particular point spreads.

Let’s take a look at every single game on the slate this week and try and predict a winner in each one against the spread.

*Point spreads courtesy of


Indianapolis Colts (-3) over JACKSONVILLE JAGUARS

The Colts are surprisingly 5-3 and in serious playoff contention, which makes it a no-brainer to take them on the road against the lowliest of all NFL teams—the Jags.

Lay the points with Luck and watch the rookie lead you to a big payday.


NEW ENGLAND PATRIOTS (-11) over Buffalo Bills

The Pats had a much-needed bye after shellacking St. Louis in London. Now they return home to Foxborough and host the 3-5 Bills—a team that kept things “close” against Houston and still lost by 12.

Considering New England stomped out this squad 52-28 back in Week 4, it’s worthwhile to lay the double-digits.


CINCINNATI BENGALS (+4) over New York Giants

Cincy is in the midst of a four-game slide, but we expect them to turn things around at home against the G-Men.

The Giants may win this one on a late field goal, so getting four points with the home team is the right call and will still result in a cover.


TAMPA BAY BUCCANEERS (-3) over San Diego Chargers

Ezra Shaw/Getty Images

The Chargers' running defense isn’t the greatest in the league, but Tampa Bay rookie RB Doug Martin shouldn’t be able to put up anywhere near the same numbers against them.

Regardless, Josh Freeman is having a renaissance season and will help lead this team to a big victory over a West Coast squad travelling a long distance for a 1:00 p.m. ET game. 


CAROLINA PANTHERS (+4) over Denver Broncos

After losing five straight, Cam Newton’s Panthers were able to turn things around against the ‘Skins.  We reckon they continue that streak by shocking Peyton Manning’s Broncos in Charlotte.

As long as Cam can avoid throwing an interception, we love Carolina’s chances to outright win this one on the money line and obviously cover the plus-four-point spread.


MIAMI DOLPHINS (-6) over Tennessee Titans

The ‘Phins have arguably one of the top defenses in the entire NFL, and should have no problem dismantling Tennessee in the same fashion that Chicago did in Week 9 (a 51-20 beat down).

Miami was on the cusp of a four-game winning streak before the Colts upset them in a close 23-20 battle, so look for a quick bounce back and a big win on Sunday.


Oakland Raiders (+7.5) over BALTIMORE RAVENS

While it’s tough to give the edge of Oakland travelling out to Baltimore, the fact of the matter is that the Raiders fought Tampa tooth and nail, despite some of the worst rush defense ever seen in an NFL game.

If they can tighten that up—and they certainly should—the Raiders will keep this game within a touchdown against an opponent with an equally shaky defense.


Scott Cunningham/Getty Images

Atlanta Falcons (?) over NEW ORLEANS SAINTS

The line for this game is not yet available. We would take the Falcons giving anywhere up to seven points against an overrated Saints squad, even with the game in NOLA.


Detroit Lions (-2) over MINNESOTA VIKINGS

These two NFC North foes are going in opposite directions, which is why we are laying the points with the streaking road squad rather than the slumping home team.

Detroit has won its past two to reach .500, while the Vikings are on a two-game skid and QB Christian Ponder is suffering a mid-season sophomore slump. Ride the momentum and take the Lions.


SEATTLE SEAHAWKS (-6.5) over New York Jets

When the Seahawks play at home, it should be required by law to take them. They are simply dominant at CenturyLink Field. Signal-caller Russell Wilson has yet to even thrown an interception in front of the home crowd.

New York is coming off a bye, but they looked absolutely atrocious going into it and their roster is an absolute shambles. Gang Green loses this by 10-plus, easily.


Dallas Cowboys (?) over PHILADELPHIA EAGLES

The line for this game is not yet available. We like the Cowboys giving up to two points on the road against Philly.


SAN FRANCISCO 49ers (-11.5) over St. Louis Rams

Ralph Freso/Getty Images

The 49ers have only allowed one opponent (the New York Giants) to score more than six points over the past five weeks.

Now they are fully rested and coming off a bye week to take on the 3-5 Rams, a team that struggles to put points on the board. We’re calling this one the lock of the week and highly suggest parlaying it with the under (38.5).


CHICAGO BEARS (-1.5) over Houston Texans

This marquee matchup pits two of the best teams in the NFL against one another. Chicago gets the edge due to its advantage at Soldier Field and riding a surge of momentum from destroying Tennessee this past week.

Houston’s strength lies in the running game, but the Bears will contain it and cover this miniscule spread.


Kansas City Chiefs (+12.5) over PITTSBURGH STEELERS

While we don’t think the Chiefs are going to keep things close with Pittsburgh, they will manage to cover this gigantic spread.

Whether it’s a late TD or FG, KC is going to backdoor cover and burst the bubble of those who decided to back the Steelers on this crazy amount of points.


Keep it tuned to B/R for all of your gambling needs and NFL information. 

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