Novak Djokovic is the favorite to win the entire tournament.
The ATP World Tour Finals kicks off Monday with an intriguing first wave of singles matches.
Headlining the annual November classic is No. 1 seed Novak Djokovic of Serbia, who will take on No. 8 seed Jo-Wilfried Tsonga of France.
Tsonga is no slouch in his own right, having achieved a No. 5 ranking earlier this year.
However, Djokovic's sights are set well beyond Tsonga and his first-round matchup, as the world's current No. 1 hopes to take down Roger Federer in the tournament.
Djokovic will handle his business against Tsonga Monday as he embarks on his quest for another title.
No. 2 Roger Federer vs. No. 8 Janko Tipsarevic
If there's anyone who can take down Djokovic, it's Federer.
The 31-year-old has intense respect for Djokovic and was quoted as saying Djokovic deserves the world's No. 1 spot for 2012 (via Bangkok Post).
With the motivation of trying to beat Djokovic in the later rounds, expect Federer to take down Tipsarevic Tuesday.
No. 3 Andy Murray vs. No. 5 Tomas Berdych
This matchup has a chance to be an exciting one considering the rather competitive history between these two.
In seven matchups, Berdych has actually come out on top four times, although Murray beat Berdych back in September to advance to the U.S. Open final.
Both players will be ready to prove they are the better of the two, and with a strong friendly rivalry in play, this first-round matchup will have a lot riding on it.
With Murray winning a gold medal at the Olympics, he's playing some of his best tennis, so expect him to come out on top against the always dangerous Berdych.
No. 4 David Ferrer vs. No. 6 Juan Martin del Potro
Who will win: David Ferrer or Juan Martin del Potro?
Another matchup with great potential will take place between the tournament's No. 4 and No. 6 seeds.
Just a week ago, Ferrer and del Potro made headlines for their impressive performances at the Valencia Open and Swiss Indoors, respectively.
Ferrer beat Ukrainian No. 1 Alexandr Dolgopolov to earn his third career Valencia Open title, and del Potro surprisingly upset Roger Federer in his 13th career title.
With both players at the top of their game, this might be the toughest first-round matchup to pick, but my money lies on Ferrer to win Tuesday.