Michael Vick, Eagles
There's no better matchup medicine for a struggling offense than the New Orleans Saints defense. Vick should eat up a defense that is allowing 475 total yards a game, and this has all the makings of a shootout. Think big for Vick, who needs a performance like this to save his job.
332 yards, 2 TDs, INT; 59 rushing yards, TD
LeSean McCoy, Eagles
If Andy Reid gives McCoy the football, he should score (and score big). Only the Bills are allowing more fantasy points per game to running backs than the Saints, who were gashed for 251 yards against the Broncos last week.
121 yards, TD; 5 catches, 35 yards
Drew Brees, Saints
Brees had an "off" game last week, throwing for just two scores and 213 yards. The Eagles aren't a pushover against the pass, but Brees always seems to save his biggest performances for primetime. He won't disappoint two weeks in a row.
314 yards, 3 TDs, INT
Pierre Thomas, Saints
The Saints know they need to run the football better on offense, and Monday night could give Thomas and Co. that opportunity. Philadelphia has allowed three straight groups of running backs to go over 100 yards.
85 yards, TD
Jeremy Maclin, Eagles
The Saints have allowed at least 30 fantasy points to opposing receivers in four straight weeks and five of seven this season. This defense simply doesn't stop receivers, and Maclin is one of the good ones. Either he or DeSean Jackson should explode Monday night.
Nine catches, 121 yards, TD