Oregon's insanely productive offense and much-improved defense dominated in a 70-14 rout over Colorado Saturday afternoon. The Ducks took a 56-0 lead into the half.
Sticking in the Pac-12, the USC Trojans were upset by the Arizona Wildcats, 39-36 despite Marqise Lee's record-breaking 16-catch, 345-yard, two-touchdown performance.
In SEC news, Georgia went into Jacksonville and upset the Florida Gators, 17-9. Florida had a chance to score a touchdown late, but tight end Jordan Reed fumbled the ball with just over two minutes remaining in the game.
Read on to see how these wins and losses effected Bleacher Report's Week 10 Top 25.
*Note: Votes are calculated with 25 points going to the No. 1 ranking, 24 points going to the No. 2, 23 points going to the No. 3 ranking and so on.