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After their win on Tuesday, Shakhtar jumped up to first place in the Group E table with seven points.
The remaining fixtures in the group favor the Ukrainian champions immensely.
The trip to Stamford Bridge in two weeks will be the toughest test left for the group leaders, but they proved on Tuesday that they are not scared of the defending European champions.
The final two matches are very winnable for the club as they will visit Denmark to play minnows Nordsjaelland and then host Juventus on the final match day.
As they have proven already, the Donbass Arena is a home fortress for Donetsk and they almost beat the Italians in Turin on match day two.
It will take something catastrophic for Shakhtar Donetsk to not advance to the knockout stage, but even the unexpected can happen in the Champions League.