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San Francisco 49ers vs. Arizona Cardinals Preview and Predictions

Aaron NaglerNFL National Lead WriterNovember 22, 2016

Frank Gore carried this San Francisco 49ers team to victory over division rivals the Seattle Seahawks. He may have to do so again when the 49ers take on the division rival Arizona Cardinals on Monday Night Football

The Cardinals were gashed by Adrian Peterson, limiting the amount of work needed to be done by quarterback Christian Ponder. You can expect a similar game plan Monday night when it comes to Gore and Kendall Hunter's workload keeping Alex Smith's contribution to a minimum. 

For the Cardinals, they simply have to work harder at getting the football into Larry Fitzgerald's hands. End-arounds, bubble screens or simple slants. Anything and everything to get one of the best players in the NFL involved in the offense. Yes, I understand there is a deficiency at quarterback. Regardless, the minimal output from Fitzgerald is borderline criminal. 

In the video above, we look at the biggest matchups and give our predictions for this big NFC West battle. Let us know what matchups you'll be watching, and give us your predictions for the game. 

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