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Tottenham Hotspur vs. Chelsea
Tottenham will likely come out flying given its recent hot streak and home-field advantage for the marquee match. As long as Chelsea can weather that early storm, the league leaders should be able to escape with at least a point.
Fulham vs. Aston Villa
One of the most surprising things about the season so far has been Fulham's potent attack, which has scored nine goals in three home matches. The Cottagers should continue to excel against a struggling Villa side.
Prediction: 2-0 Fulham
Liverpool vs. Reading
Liverpool would have liked to earn more than a draw against Stoke City in its last match, but the Reds' overall level of play recently has been encouraging. A victory over Reading would finally start to put some distance between them and the relegation zone.
Prediction: 2-1 Liverpool
Manchester United vs. Stoke City
Even though there's still room to improve, United's lineup featuring both Robin van Persie and Wayne Rooney has started to settle in and looks extremely dangerous. The Red Devils should have no problem cruising past a middling Stoke squad at home.
Prediction: 3-0 Manchester United
Swansea City vs. Wigan Athletic
Swansea has been able to hold its own thanks to strong play from underrated options like Michu and Wayne Routledge. That said, the Swans face a tricky test in a Wigan side that should be riding high after earning a draw with Everton.
West Bromwich Albion vs. Manchester City
This match will be a great measuring stick for both teams. It will illustrate whether or not West Brom can continue playing at a top-six level and also show if City has found the form that allowed it to win last season's title. It should be a terrific clash.
Prediction: 1-0 Manchester City
West Ham United vs. Southampton
If Southampton would have received even average defending through the first seven matches, it would be around the middle of the table. Instead, the Saints have been doomed by a weak back line, and West Ham will take advantage of that weakness.
Prediction: 2-1 West Ham United
Norwich City vs. Arsenal
Although Arsenal is only sitting in seventh place right now, the Gunners are definitely trending in the right direction, as their new players are starting to show why Arsene Wenger brought them in. Norwich has struggled at home with 11 goals against in four games.
Prediction: 3-1 Arsenal