In what should be an unpredictable week of football, there are a couple of games that stand out as safe bets.
Sunday features only one divisional game, and the unfamiliarity between the teams makes things interesting. This is also a big week for home teams, as all but two are favored on Sunday.
However, there are a couple of easy picks available if you follow the trends.
Note: All lines courtesy of Vegas Insider.
New York Giants (+6.5) over San Francisco 49ers
This should be a highly competitive game between two of the best teams in the NFC. The 49ers have an incredible defense that will be tough to score on, but the Giants counter with the No. 2 offense in football.
New York struggles at times defensively, but Alex Smith is unlikely to take advantage of a poor secondary. This should prevent the 49ers from being able to put a lot of points on the scoreboard.
With a relatively high point spread, the Giants should be able to do enough to keep this game close.
Kansas City Chiefs (+4) over Tampa Bay Buccaneers
Cassel also had a knack for turning the ball over, with nine interceptions already this season. Hopefully for the Chiefs, backup Brady Quinn will be more careful with the football.
Tampa Bay has lost three straight games since its Week 1 win over the Carolina Panthers. The games have been close, but the team has been below average on both sides of the football.
This should be a good opportunity for the Chiefs to get their second win of the season.
Minnesota Vikings (+1.5) over Washington Redskins
On the other side, the Vikings look like legitimate contenders after a 4-1 start. Adrian Peterson has reverted to old form and Christian Ponder is playing better than many anticipated with a 95.5 quarterback rating.
Robert Griffin III is listed as questionable after sustaining a concussion last week, but even if he plays, he will struggle against the athletic front seven of Minnesota's defense. If he sits, this game will be over quickly.
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