Though there is still no official word on Nicks' status, that's an encouraging sign for the Giants. However, savvy fantasy football owners will take that as a great sign moving forward instead of an opportunity to deploy Nicks in Week 6.
A matchup against the vaunted San Francisco 49ers defense is on tap and injury questions are boundless, so there is just too much risk with not nearly enough reward.
With that in mind, here's a look at the most glaring reasons Nicks should be on your bench this week, regardless of playing status.
We Have No Idea How Many Snaps Nicks Will Play (If He Plays)
Though he was back in practice on Thursday, Nicks was still on the field in a very limited basis.
If we try to read anything into that, it would stand to reason that the Giants would keep his number of snaps to a minimum.
It's also not as if Nicks has injuries that will allow him to be 100 percent anytime soon. Both his foot and knee are seemingly recurring problems that could last throughout the remainder of the regular season.
All it will take is one tweak of the muscle or one awkward step and Nicks will be back on the sidelines. Until we see that he can be an every-down receiver again, the possibility of an injury recurrence is far too big of a risk.
The 49ers Defense Has Been Dominant Against the Pass
Coming into Week 6, San Francisco's defense has lived up to its high-profile billing in every way.
The unit leads the league in points per game allowed with just 13.6 and ranks No. 2 behind the Seattle Seahawks in total defense, giving up a paltry 262.6 yards per contest.
Vital to that cause has been a stingy pass defense, which is the best in the NFL among teams that have played in all five weeks.
What's more, San Francisco has been even better than advertised lately, giving up a paltry three points and forcing six turnovers in the past two weeks.
While the Giants have a strong offense and will undoubtedly get into the end zone on Sunday, it seems highly unlikely anyone on the roster will be a top-notch fantasy play.
Kickoff is Not Until 4:25 p.m. ET
With word on Nicks' status almost certainly coming down to a game-time decision, the fact that is an afternoon game is paramount.
Had the Giants and 49ers been facing off at 1 p.m., fantasy owners would have received notice in plenty of time and been able to substitute from the bench or make a pickup in free agency.
The late start handcuffs owners into the worst possible scenario. By playing in a late game, the Giants wideout is vastly limiting the pool of replacements owners can choose from if he sits out on Sunday.
Obviously, you're planning on starting Nicks over a player with a late Sunday or Monday night kickoff, then this is not a worry.
However, if his status has any influence on a player's lineup spot that is playing at 1 p.m., sit Nicks and save yourself the worry.