The Mexican team sits atop group B of the COMCACAF qualification for the World Cup at Brazil 2014, with their next opponent Guayana only taking one point from their opening four matches of the qualification process.
With Costa Rica and El Salvador also vying to advance from the group phase in order to preserve the dream of playing at the next World Cup, El Tri must apply professionalism against the Golden Jaguars.
Here is a comprehensive preview of the upcoming World Cup qualification match that will be crucial for El Tri to advance.
Where: BBVA Compass Stadium, Houston, Texas
When: Friday, 9 p.m. EDT
TV/Live Steam: Telemundo (Español)
Guyana Manager: Jamaal Shabazz
Colin Edwards (Caledonia AIA), Richard Reynolds (Alpha United FC), Ronson William (Alpha United FC).
Colin Nelson (Caledonia AIA), J.P. Rodrigues (Tampa Bay Rowdies), Walter Moore (Caledonia AIA), Jamaal Smith (Syrianska), Leon Cort (Charlton Athletic), Charles Pollard (North East Stars), Taylor Benjamin (Capital City FC).
Dwain Jacobs (Alpha United FC), Howard Newton (Staines Town), Konata Mannings (Pele FC), Kayode McKinnon (Antigua Barracuda FC), Trayon Bobb (Caledonia AIA), Nick Millington (Carolina Railhawks), Ricky Shakes (Kidderminster), Shawn Beveney (Caledonia AIA), Chris Nurse (Puerto Rico Islanders).
Carl Cort (Tampa Bay Rowdies), Gregory Richardson (Puerto Rico Islanders), Vurlon Mills (United Petrotin), Sheldon Holder (Alpha United FC).
Mexico Manager: Jose Manuel de la Torre
Alfredo Talavera (Toluca), Jonathan Orozco (Monterrey).
Adrian Aldrete, Diego Reyes (both América), Francisco Rodriguez (Stuttgart), Severo Meza (Monterrey), Hector Moreno (Espanyol), Joel Huiqui (Morelia), Israel Jimenez and Jorge Torres Nilo (both Tigres).
Carlos Peña (León), Andres Guardado (Valencia), Angel Reyna (Monterrey), Jorge Enríquez (Guadalajara), Hector Herrera (Pachuca), Sinha (Toluca), Gerardo Torrado and Javier Aquino (both Cruz Azul).
Elias Hernandez (Tigres), Oribe Peralta (Santos Laguna), Aldo de Nigris (Monterrey), Javier Hernandez (Manchester United).
Diego Reyes arrived as a fully fledged international player when Mexico won the gold medal this summer at the London 2012 Olympics.
The Club America defender is a prodigious talent who can flourish for the Mexico side over the coming months and years with an uncanny ability to intercept the ball. Having been featured mostly at centre-back for the Águilas in recent months, Reyes is equally adept at playing in a central-midfield role.
Francisco Javier Rodriguez aside, El Tri's squad possesses limited experience at the back, so tremendous faith has been placed on Reyes to prove he can lead La Verde to senior titles after recent success at the youth level.
Shawn Beveney is an attacking midfielder who plays for one of the minnows of English football, Cray Wanderers, and has played 41 times for Guayana, scoring 22 times.
Beveney, who has played the majority of his career with semi-professional clubs, will have to play like he never has before if the Golden Jaguars are to even make like difficult for El Tri.
Mexico posted an easy 3-1 victory in the last meeting between the two sides. Guyana must put up a resilient display on defense and hope that Beveney can conjure up some magic on the counter attack.
Guyana (4-4-2): Goalie Reynolds; Pollard, Leon Cort, Rodrigues, Moore; Shakes, Nurse, Bobb, Millington; Richardson, Carl Cort
Mexico (4-2-2-2): Goalie Talavera; Torres Nilo, Moreno, Rodriguez, Meza; Torrado, Enriquez; Guardado, Aquino; Peralta, Hernandez
The main contention for Jose Manuel de la Torre will be whether to throw the youngsters into the side from the start, after selecting an inexperienced squad that included Diego Reyes (America), Jorge Enriquez (Guadalajara) and Javier Aquino (Cruz Azul) who combine for fewer than 20 caps together.
The uncapped duo of Hector Herrera (Pachuca) and Carlo Peña (Leon) will also be looking for a place in the side as "El Chepo" looks to create a team capable of winning in Brazil in two years.