The Potters will provide a tough challenge for Liverpool, having lost only once so far, and will look to make the most of any tired legs after the team's Europa League game against Udinese. That is, of course, if Brendan Rodgers doesn't rest a number of starters.
Stoke currently sits 12th in the league with Liverpool two spots behind at 14th and this should be an intriguing battle between two very different styles.
Here's the team news and projected lineups for this game.
Liverpool Team News
According to PhysioRoom.com, Liverpool will be hoping that both Joe Cole and Jose Enrique can reach full fitness for Sunday's match but Martin Kelly and Lucas Leiva are still long-term absences.
Luis Suarez has started to find his form and scored a hat-trick against Norwich, and loan-signing Nuri Sahin has also started to look better.
One worry for Brendan Rodgers is the team's inability to keep a clean sheet in the Premier League and that is something he will certainly be looking for this weekend.
Projected Starting XI (4-3-3)
Stoke City Team News
Stoke City has no real injuries to speak of, so Tony Pulis should have no problem picking the right squad for this game.
One of the players in contention is former Liverpool man Charlie Adam, who will have something to prove as he faces his old side.
Stoke's lack of potency in front of goal continues with only six goals in five games. It has also conceded five goals.
Projected Starting XI (4-4-1-1)