With Darrelle Revis out for the rest of the season with a torn ACL, it's time to review the worst injuries thus far this season.
For the sake of this article, we'll be chronicling the most devastating injuries that have affected this season.
While Revis' injury makes for a huge loss, other players' injuries have left their teams equally crippled.
A torn pectoral muscle for Brian Orakpo ended the star linebacker's season early in 2012, downing the Washington Redskins' renewed hope.
Unfortunately for the Redskins, the team also lost pass-rusher Adam Carriker and has looked pedestrian on defense in 2012 thus far.
After allowing 31 points to the St. Louis Rams, the team turned around and allowed 38 points to the Cincinnati Bengals.
Austin Collie, one of the most frequently injured players in the league, looks to miss the rest of the season, thanks to a nasty knee injury for the Indianapolis Colts.
Collie has suffered various bumps and bruises in his time in the league, but he'll now lose the rest of his year to this malady.
Andrew Luck needs all of his receivers healthy if he is to thrive, so losing Collie doesn't bode well for the rookie quarterback.
Early in the preseason, the Cincinnati Bengals lost star offensive lineman Travelle Wharton to an unfortunate torn ACL.
The Bengals have the offensive line depth to replace Wharton, but they were looking to run behind this behemoth all season long.
Losing Wharton doesn't derail Cincinnati's plans for 2012, but it certainly hurts a team trying to gain legitimacy in a tough AFC North.
Suffering from a torn ACL, New York Jets cornerback Darrelle Revis will miss the rest of the season, which severely cripples a defense that looked good thus far.
The Jets game plan around Revis and won't have the luxury of leaving a cornerback on a man-coverage island every play.
Rex Ryan will need to be a lot more conservative now, which could kill his defensive style.
The one knock on Adrian Clayborn coming out of college was his proneness to injury, and that has manifested itself following a season-ending knee injury.
Clayborn was the best pass-rusher on the Tampa Bay Buccaneers and losing this defensive end will certainly hurt Greg Schiano's unit.
The former Iowa standout has all the tools to be successful in the league, but he needs to stay on the field.
After tearing his pectoral muscle against the Buccaneers in Week 3, Dallas Cowboys safety Barry Church will miss the rest of the season.
It's unfortunate, considering Church had carved himself a solid niche as the starting safety in a deep defensive backfield.
Rob Ryan will have to adjust his schemes to account for the loss of this hard hitter. Look for the Cowboys to frantically search for a replacement.