Just like real life, injuries can be the downfall of any football team—especially in fantasy land. As the early games play on, there is still time to adjust your rosters for the late games.
Here are some late-game injuries that will impact your fantasy team in one way or another:
Troy Polamalu and James Harrison
Pittsburgh is usually one of the first defenses off the board come draft night. However, with an aging defense and cornerbacks who are suspect, the loss of not only James Harrison but also Troy Polamalu will turn Sunday's game against the New York Jets into a shootout.
Ben Roethlisberger will be forced to put up 25 points to defeat the Jets because of Polamalu's and Harrison's injuries.
What seemed to be a great matchup for the Steelers defense prior to the Jets' 48-point explosion against the Bills appears to be a game that could be played in the high 20s.
Jake Locker Will Start Against San Diego
According to ESPN's John Clayton, Jake Locker will start at San Diego.
In a deep league, Locker may be your starter. He went 23-of-32 for 229 yards against the New England Patriots in Week 1.
Locker's ability to run the ball should open more holes for running back Chris Johnson. If you have the running back, expect more contributions from him against a team he has played well against in his career.
Will the Redskins lose on Sunday?
Johnson has recorded two touchdowns against the Chargers in two games played. Locker's ability to do multiple things on the field should open more holes for Johnson to operate.
Pierre Garcon Is Out for the Game Against the Rams
One of Robert Griffin's favorite targets in Week 1 was Pierre Garcon. Now that Garcon won't suit up Sunday in St. Louis (per ESPN.com), who does he choose to go to now?
St. Louis' pass defense forced three Matthew Stafford interceptions last week in Detroit. Coach Jeff Fisher has drastically improved the Rams pass defense, and now St. Louis has an opportunity to slow down Griffin minus Garcon, who caught four passes for 109 yards and a touchdown in Week 1.
Fantasy owners could use Santana Moss, Aldrick Robinson or Josh Morgan this week, as these three receivers should garner more looks from Griffin.