The match will start at 4 p.m. ET on CBS, as noted by USOpen.com.
Murray escaped a match against Roger Federer when Tomas Berdych upset the Swiss. He then took care of Berdych to reach the final. Djokovic predictably made it through his side of the bracket.
Here is what to watch for in the final match at Flushing Meadows.
Murray’s Slow Start
Murray lost the first set in both the quarterfinals against Marin Cilic and the semifinals against Berdych.
Against Cilic, the Scotsman was down 5-1 in the second set before finally finding his rhythm and settling down. From that point on, he dominated the match.
In the next round, Berdych took the first set 7-5, but Murray came back to dominate the middle of the match and took a 2-1 lead. He then closed out his opponent in a thrilling final set.
But Djokovic will not be as forgiving if Murray does not warm up until the second set. A slow start may doom the Scot to another loss in the finals at a major.
Djokovic on Hard Courts
It has been two full years since another player has won a Grand Slam on hard courts.
Djokovic has won the last two Australian Opens as well as the 2011 U.S. Open. This has given him 27 consecutive victories on hard courts at majors, as noted by the BBC.
The fast courts at Flushing Meadows allow Djokovic’s elite athleticism and reflexes to show. When the tempo picks up in matches against the Serb, he is nearly impossible to beat.
Given Djokovic’s history on hard courts, he will be a incredibly difficult challenge for Murray.
Who will win?
The Monkey on Murray’s Back
This is Murray’s fifth time in the finals at a major, but he has lost in all four of his previous appearances.
His most recent loss was to Federer in the finals at Wimbledon this year, but Murray followed up that disappointing defeat with a gold-medal winning performance at the London 2012 Olympics.
Now, he carries more momentum into this match than he has at any of his other finals appearances.
Murray has been just outside of the elite group of men’s tennis players, and this represents his best chance to prove that he belongs in the same sentence as Federer, Djokovic and Rafael Nadal.