While the Jets' preseason woes have been well documented, Sanchez was quietly efficient and accurate.
Everyone remembers his costly interception against the Giants, but he was also 9-for-11 in that game, despite being under pressure for the entire half.
Historically, Sanchez has been effective against the Bills (save for his rookie season five-interception performance), as ESPN's Rich Cimini points out:
It should be noted that one of those games was the 2010 Week 17 machup in which he played one series consisting of straight handoffs, but even two interceptions in three games is above his average turnover ratio.
How to keep him effective
Obviously, none of these stats will matter if the Jets cannot slow down the Bills' pass rush. The Jets need to give Austin Howard help with Mario Williams, and D'Brickashaw Ferguson needs to play like his old self.
At the same time, the Jets receivers need to gain separation, which is something the injury-plagued unit did not do in the preseason. Making clear, defined targets for Sanchez will be key against a solid Bills secondary. Having Holmes and Kerley back in the lineup should go a long way in improving the receiver production.
One aspect that should not be overlooked is Sanchez's habit of holding the ball with one hand. Odds are, the Bills are going to get a few sacks on Mark, but he cannot allow a drive-killing sack to turn into a devastating turnover with a strip-sack.
Ball security during dropbacks is just as, if not more important than not throwing interceptions; at least during interceptions, the ball is (usually) down the field.