As we enter the second week of U.S. Open competition from Flushing Meadows, the storylines that we thought we would be talking about have given way to new, unexpected surprises that will make for an interesting final week. 

With just 20 men remaining in the field, it is time to look at the readjusted odds and determine who is going to be playing for the final Grand Slam championship of 2012. 

Odds courtesy of Bovada

PLAYER ODDS
 Novak Djokovic  5/4
 Roger Federer   9/4
 Andy Murray   7/2
 Juan Martin Del Potro  11/1
 Tomas Berdych  40/1
 John Isner  40/1
 Milos Raonic  40/1
 David Ferrer  50/1
 Mardy Fish  100/1
 Marin Cilic  100/1
 Andy Roddick  100/1
 Richard Gasquet  150/1
 Janko Tipsarevic  150/1
 Alexandr Dolgopolov  200/1
 Stanislas Wawrinka  200/1
 Fernando Verdasca  300/1
 Nicolas Almagro  300/1
 Philipp Kohlschreiber  300/1
 Lleyton Hewitt  500/1
 Julien Benneteau  500/1

 

Biggest Lock: Novak Djokovic

Hi-res-151075337_crop_exact Matthew Stockman/Getty Images

When the U.S. Open draw first came out, it seemed designed to get Novak Djokovic into the finals. He didn't have to go through Andy Murray or Roger Federer, and the best ranked opponents he could play prior to that is No. 7 Juan Martin del Potro in the quarterfinals and No. 4 David Ferrer in the semi-finals. 

He has yet to drop a set through his first two matches, never losing more than two games thus far. If he doesn't get to the finals, it will be a monumental upset. 

 

Sentimental Favorite: Andy Roddick

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Before the U.S. Open started, Roddick was a lost thought. He did have two singles titles in 2012, but his overall mark was a pedestrian 18-15 and he had just three match wins in the first three Grand Slam events. 

Then, out of nowhere, Roddick announced that he was retiring after this event. Now, while the odds are still stacked against him, everyone is talking about Roddick, hoping to see him do well in his final event. 

Obviously, expecting a win will lead to disappointment, but there is interest and anticipation whenever he steps on the court for the first time in nearly a decade. 

 

Underdog Who Could Surprise: John Isner

Isner_original Courtesy of Al Bello, Getty Images

It says a lot about the state of men's tennis where the No. 10 player could be considered an underdog, but the sport is so top heavy that after the Big Three you have a lot of uncertainty. 

Isner has the benefit of not playing David Ferrer until the quarterfinals, assuming both men continue to advance. 

Playing Djokovic in the semifinals is the biggest obstacle standing in his way. If he can figure out a way to conquer that mountain, he will have all the confidence he needs to win his first Grand Slam.