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The Giants defensive line was a key factor in both of their victories over the Cowboys last season. The unit racked up nine sacks, and they were able to put constant pressure on Tony Romo.
Romo did exploit the Giants secondary, however, and I do believe that he has the capabilities to do so once again this season. The only thing that may prohibit Romo from doing so is the Cowboys failure to upgrade the offensive line. The line has not had enough time to play together as a unit yet, which is a big problem when you're playing a defensive line that is as good as the Giants.
Guard Nate Livings missed most of the preseason with a hamstring injury, while fellow guard Mackenzy Bernadeau missed the entire offseason and a decent amount of camp after knee and hip surgeries. Center Phil Costa only played in one preseason game after he hurt his back.
If the Cowboys offensive line can give Tony Romo enough time to work through a depleted Giants secondary, then Dallas may win the first game against New York since November 14, 2010.
Edge: Giants defensive line