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While the rushing numbers were great, you have to remember that the Titans were playing the Buccaneers.
The interior of the Tennessee O-line still looked suspicious at times.
There were a lot of missed blocks. It's hard to tell who messed up when, but there were several times in the game that some interior defensive linemen went through untouched.
There was also trouble with the run blocking. Now, I am aware that the Titans had 216 total rushing yards, but that is due, mostly, to a combination of a few big runs by Chris Johnson and Darius Reynaud and terrible Buccaneers defense.
Chris Johnson's first few runs, and several more early in the game, got stuffed because he had nowhere to run. When he was running off the edge of the tackles, he did just fine, but when he had to go up the middle, he got shut down.
Jamie Harper experienced similar problems.
The Titans have to spend some early picks in next year's draft on interior linemen. It will be a problem this season, and it needs to be fixed as soon as possible.