Will Mathews ever stay healthy?
In his first carry of the 2012 preseason, Mathews suffered a broken clavicle. He was expected to have a monster year in 2012, but his injury means that he will miss the beginning of the regular season. Mathews' absence will be a huge hindrance to the Chargers' offense. Moving forward, the Chargers' organization and their fans will always wonder whether Mathews will be able to remain healthy.
Can Brown handle being a starting running back?
It appears as if Brown will be forced to start at least one game during the regular season due to Mathews' injury. Brown used to be a very good running back, but his performance with the Philadelphia Eagles last season was absolutely terrible. Fortunately, Brown has been very impressive during training camp. For the Chargers to come out of the gates fast in 2012, Brown will have to produce.
Will Battle take advantage of his opportunity?
When Battle was signed, the Chargers already had a log jam at running back. His signing only made the backup running back situation more complicated. Following Mathews' injury, Battle has the opportunity to show that he deserves carries during the regular season. If he performs well, he could potentially be the main running back at the start of 2012. If he disappoints, he could find himself out of an NFL job.
Will Brinkley's familiarity with the Chargers keep him on the roster?
Brinkley is not as big of a name as Brown or Battle, but he has been a solid running back for the Chargers. His familiarity with the playbook might help keep him on the team.
Did Baker make a poor decision leaving school early?
Despite being selected by the Chargers, Baker has not been as impressive as fellow rookie Michael Hayes. It looks like Baker should have stayed at Michigan State.
Will the coaching staff believe in an undrafted rookie?
Hayes entered training camp with least fanfare out of the running backs, but he has been very impressive during training camp. If the coaching staff gains enough confidence in Hayes, there is a chance that he could make the roster over Battle, Brinkley and Baker.